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3 Feb, 26
This IDSA guideline outlines evidence‑based empiric and definitive antibiotic selection for complicated UTI, emphasizing severity‑based therapy, resistance risk assessment, patient‑specific factors, and stewardship‑driven narrowing once cultures return.
3 Feb, 26
11 Feb, 26
Diabetes Obes Metab.
- The link between time in target range for BMI (TTR-BMI) was evaluated in a pooled analysis of 9167 adults aged ≥45 y
- A higher TTR-BMI reduced cardiometabolic multimorbidity (CMM), each 1-SD rise in TTR-BMI lowered CMM risk by ~10%, “always in range” (TTR=1) had 23.8% lower CMM risk
- The inverse link was most explicit particularly in those with coexisting diabetes & dyslipidemia (HR 0.76), in men & in those ≥60 y.
11 Feb, 26J Crit Care.
- Fast serum sodium (SNa) correction (>0.5 mmol/L/h) within the first 24 h in critically ill patients with severe hypernatremia reduced 30 day mortality (HR 0.49) and improved 30-day hospital free survival (HR 1.75) vs. slow SNa correction (≤0.5 mmol/L/h)
- It also shortened ICU stay (4 vs 5 days, p = 0.002) and hospital length of stay (8 vs 11 days, p = 0.01)
10 Feb, 26Pediatr Infect Dis J...
- Pediatric rhinovirus infections rose nearly three-fold across two seasons (2024 to 2025: 0.42 vs. 1.22 cases/day), but clinical severity remained stable
- Fever, cough and rhinorrhea and antibiotic use declined (60% to 48.9%)
- Hospitalization rates were unchanged, chest X ray use (34.8% to 49.7%) and coinfections increased (3.5% to 10.2%) but did not affect outcomes.
9 Feb, 26Respir Med
- COPD and heart failure frequently coexist but remain undiagnosed
- In specialized clinics, unrecognized HF in COPD was 26.1%, and unrecognized COPD in HF was 26.8% and these patients were older, mostly male, and heavy smokers
- Abnormal echocardiography/spirometry increased exacerbation like events (1.3 vs 0.6 in COPD; 16.7% vs 6.3% in HF)
- No specific biomarkers reliably distinguished overlap disease.
5 Feb, 26
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11 Feb, 26
11 Feb, 26
11 Feb, 26
