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3 Feb, 26
This IDSA guideline outlines evidence‑based empiric and definitive antibiotic selection for complicated UTI, emphasizing severity‑based therapy, resistance risk assessment, patient‑specific factors, and stewardship‑driven narrowing once cultures return.
3 Feb, 26
12 Feb, 26
Endocr Pract.
- In 23576 women (24–28 wks gestation) undergoing 75 g OGTT, 7.07% had hypoglycemia (<3.9 mmol/L)
- Hypoglycemic women were younger, had lower BMI & their neonates showed low birth weight (LBW), incidence of larger for gestational age (LGA)/macrosomia was lower & that of LBW & SGA was higher in the neonates born to these women
- Close monitoring in these women is essential to alleviate adverse perinatal outcomes.
11 Feb, 26Diabetes Obes Metab.
- The link between time in target range for BMI (TTR-BMI) was evaluated in a pooled analysis of 9167 adults aged ≥45 y
- A higher TTR-BMI reduced cardiometabolic multimorbidity (CMM), each 1-SD rise in TTR-BMI lowered CMM risk by ~10%, “always in range” (TTR=1) had 23.8% lower CMM risk
- The inverse link was most explicit particularly in those with coexisting diabetes & dyslipidemia (HR 0.76), in men & in those ≥60 y.
11 Feb, 26J Crit Care.
- Fast serum sodium (SNa) correction (>0.5 mmol/L/h) within the first 24 h in critically ill patients with severe hypernatremia reduced 30 day mortality (HR 0.49) and improved 30-day hospital free survival (HR 1.75) vs. slow SNa correction (≤0.5 mmol/L/h)
- It also shortened ICU stay (4 vs 5 days, p = 0.002) and hospital length of stay (8 vs 11 days, p = 0.01)
10 Feb, 26Pediatr Infect Dis J...
- Pediatric rhinovirus infections rose nearly three-fold across two seasons (2024 to 2025: 0.42 vs. 1.22 cases/day), but clinical severity remained stable
- Fever, cough and rhinorrhea and antibiotic use declined (60% to 48.9%)
- Hospitalization rates were unchanged, chest X ray use (34.8% to 49.7%) and coinfections increased (3.5% to 10.2%) but did not affect outcomes.
5 Feb, 26
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11 Feb, 26
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