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30 Jul, 26
The second Universal Definition of heart failure (HF) standardizes HF terminology, reclassifies HF phenotypes beyond rigid EF cutoffs, emphasizes pre-HF detection, social determinants, & global disparities to improve prevention, diagnosis, & care.
14 Jul, 26
ESHRE 2026
Key highlights of the sessions on global and socio-cultural aspects of infertility presented at ESHRE from 5th to 8th July 2026 in London, UK.
11 Aug, 26Diabetes Res Clin Pr...
- In a multi-ethnic cohort of 352 youth with T1DM, 29.5% had BMI ≥85th percentile & 10.7% of them were obese (BMI >95th percentile)
- Higher weight-adjusted total daily insulin dose was independently linked to overweight/obesity, suggesting raised insulin resistance but the association lost its significance when adjusted for obesity
- Identifying modifiable risk factors may improve obesity prevention in youth with T1DM.
10 Aug, 26Front. Pediatr.
- In 70 children with aplastic anemia (AA), 2-yr overall survival was 97.1% & event-free survival was 48.5% after 60.7 mos
- Severe/very severe AA achieved a higher 2-yr overall response rate than nonsevere AA (85.5% vs 55.6%)
- HSCT achieved faster & higher complete response rates & superior event-free survival vs immunosuppressive therapy (IST); eltrombopag (EPAG) induced complete responses in 2 therapy-resistant pts.
7 Aug, 26Diabetes Obes Metab.
- The link between time in range (TIR; the core CGM metric), & advanced CKM syndrome was ascertained in 2497 adults ≥60 years with T2DM
- Lower CGM TIR was independently associated with advanced CKM syndrome (stages 3-4), each 1-SD decrease in TIR raised odds by 28% (OR 1.28, 95% CI 1.16-1.42)
- Risk rose across TIR categories, with TIR 50-70% vs >70% linked to higher CKM odds (OR 1.40), without increased hypoglycemia.
6 Aug, 26JAMA Cardiol.
- Treadmill stress testing (TST) safely identified occult symptoms/AVR indications in 15% of patients with asymptomatic severe aortic stenosis (AS)
- Among 105 registry patients (mean age 76.1 yrs, 76.2% male), 2-yr mortality was 5.7%; AVR rates: 79.9% at 1 yr & 85.9% at 2 yrs
- Positive TST predictors included higher peak velocity, lower EF, prior CABG, & stroke
- Despite indications, ~20% remained untreated at 1 yr.
4 Aug, 26
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3 Aug, 26
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27 Jul, 26
